Physiological responses to folate overproduction in Lactobacillus plantarum WCFS1
نویسندگان
چکیده
منابع مشابه
Physiological responses to folate overproduction in Lactobacillus plantarum WCFS1
BACKGROUND Using a functional genomics approach we addressed the impact of folate overproduction on metabolite formation and gene expression in Lactobacillus plantarum WCFS1. We focused specifically on the mechanism that reduces growth rates in folate-overproducing cells. RESULTS Metabolite formation and gene expression were determined in a folate-overproducing- and wild-type strain. Differen...
متن کاملLactobacillus plantarum WCFS1 electron transport chains.
Lactobacillus plantarum WCFS1 requires both heme and menaquinone to induce respiration-like behavior under aerobic conditions. The addition of these compounds enhanced both biomass production, without progressive acidification, and the oxygen consumption rate. When both heme and menaquinone were present, L. plantarum WCFS1 was also able to reduce nitrate. The ability to reduce nitrate was sever...
متن کاملComplete genome sequence of Lactobacillus plantarum WCFS1.
The 3,308,274-bp sequence of the chromosome of Lactobacillus plantarum strain WCFS1, a single colony isolate of strain NCIMB8826 that was originally isolated from human saliva, has been determined, and contains 3,052 predicted protein-encoding genes. Putative biological functions could be assigned to 2,120 (70%) of the predicted proteins. Consistent with the classification of L. plantarum as a ...
متن کاملComplete resequencing and reannotation of the Lactobacillus plantarum WCFS1 genome.
There is growing interest in the beneficial effects of Lactobacillus plantarum on human health. The genome of L. plantarum WCFS1, first sequenced in 2001, was resequenced using Solexa technology. We identified 116 nucleotide corrections and improved function prediction for nearly 1,200 proteins, with a focus on metabolic functions and cell surface-associated proteins.
متن کاملPopulation heterogeneity of Lactobacillus plantarum WCFS1 microcolonies in response to and recovery from acid stress.
Within an isogenic microbial population in a homogenous environment, individual bacteria can still exhibit differences in phenotype. Phenotypic heterogeneity can facilitate the survival of subpopulations under stress. As the gram-positive bacterium Lactobacillus plantarum grows, it acidifies the growth medium to a low pH. We have examined the growth of L. plantarum microcolonies after rapid pH ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Microbial Cell Factories
سال: 2010
ISSN: 1475-2859
DOI: 10.1186/1475-2859-9-100